Aplenc Lab at the 2024 Annual American Society of Hematology Meeting & Exposition

The 2024 American Society of Hematology (ASH) Meeting and Exposition will take place December 7-10, 2024, in San Diego, California, and online. The symposium will feature 7 abstracts submitted by Dr. Aplenc, his research team, and close collaborators.

Molecular Characteristics Influencing Relapse Risk in Low-Risk Pediatric Acute Myeloid Leukemia

Lusha Cao, Yang Xu, Tina Glisovic-Aplenc, Han R Fisher, Saamia Farooki, Kelly D. Getz, Todd A. Alonzo, Alan S Gamis, Soheil Meshinchi, Yi Xing, and Richard Aplenc

Program: Oral and Poster Abstract, Acute Myeloid Leukemias: Biomarkers and Molecular Markers in Diagnosis and Prognosis

Poster Session: December 8, 6-8 PM PST | Session 618 (Number 2932)

Serum-Based Proteomic Analysis of Cytokine Release Syndrome in Pediatric AML Patients Receiving CART123

Saamia Farooki, Han R Fisher, Anand S Bhagwat, Tina Glisovic-Aplenc, Lusha Cao, Regina M. Myers, Haley Newman, Caroline Diorio, Saar Gill, and Richard Aplenc

Program: Oral and Poster Abstracts, Acute Myeloid Leukemias: Biomarkers and Molecular Markers in Diagnosis and Prognosis

Poster Session: December 8, 6-8 PM PST | Session 618 (Number 2946)

Near Universal National Uptake of Dexrazoxane in the Real-World Setting Associated with Reduced Cardiac ICU Care Requirements in Pediatric Acute Myeloid Leukemia

Daniel J. Zheng, Gary Hettinger, Lusha Cao, Caitlin W. Elgarten, Brian T. Fisher, Cody Gathers, Yuan-Shung V. Huang, Jennifer Ko, Kasey Leger, Yimei Li, Regina M. Myers, Hari K. Narayan, Jose Ortiz, Alix E. Seif, Richard Aplenc, Kelly D. Getz.

Program: Oral and Poster Abstract, Outcomes Research: Myeloid Malignancies: Identifying Problems and Providing Solutions to Delivering Myeloid Malignancy Care

Poster Session: December 7, 9:45 AM PST | Session 908 (Number 116)

Real-World Generalizability of Clinical Trial Cytomolecular Features By Race and Ethnicity in Pediatric Acute Myeloid Leukemia (AML)

Daniel J. Zheng, Gary Hettinger, Catherine Aftandilian, Kira Bona, Emi H. Caywood, Anderson B. Collier, Caitlin W. Elgarten, Cody Gathers, Taumoha Ghosh, Maria Monica Gramatges, Meret Henry, Yuan-Shung V. Huang, Yimei Li, Craig Lotterman, Kelly Maloney, Amir Mian, Tamara P. Miller, Arunkumar Modi, Rajen Mody, Elaine Morgan, Regina M. Myers, Haley Newman, Alix E. Seif, Caroline Smith, Jamie Stokke, Naomi J. Winick, Jennifer J. Wilkes, Victor Wong, Richard Aplenc, and Kelly D. Getz.

Program: Oral and Poster Abstract, Outcomes Research: Myeloid Malignancies: Social and Economic Disparities in Treatments, Outcomes and Financial Toxicity

Poster Session: December 8, 9:30-10:30 AM PST | Session 908 (Number 531)

Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia

Francisco Marchi, Ann-Kathrin Schade, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Jeffery M Klco, Alan S Gamis, Rhonda E. Ries, Anders Kolb, Richard Aplenc, Todd A. Alonzo, Stanley Pounds, Soheil Meshinchi, Jatinder K. Lamba.

Program: Oral, Emerging Tools, Techniques, and Artificial Intelligence in Hematology Program: Oral and Poster Abstracts

Session: December 7, 9:30 AM PST | Session 103

Autologous CD33CART for Children and Adolescents/Young Adults with Relapsed/Refractory AML: Phase 1/2 Clinical Trial Correlative Biology Analyses Demonstrate Potent in Vitro, In Vivo, and Ex Vivo Anti-Leukemia Activity

Tommaso Balestra, Camilo Arenas Merizalde, Robert K Chen, John Roach, Brian Bowser, Rachelle Salomon, Anthony Welch, Bonnie Yates, Kristin Schaller, Michael R Verneris, Susanne H.C. Baumeister, Emily M. Hsieh, M. Eric Kohler, Katherine Tarlock, Steven Michael Devine, Richard Aplenc, Nirali N. Shah, Terry J Fry, and Sarah K Tasian

Program: Oral and Poster Abstracts, CAR-T Cell Therapies: Basic and Translational: Myeloid Biology and CAR-T Cells

Poster Session: December 7, 4:30 PM PST | Session 702 (Number 369)

A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO – a Report from the Children’s Oncology Group

Betsy Hirsch, Gordana Raca, Kasey Leger, Jennifer J. Wilkes, Aman Wadhwa, Zachary Graff, Reena Pabari, Samir Kahwash, Karen M Chisholm, Joseph Chewning, John T. Horan, Richard Aplenc, Katherine Tarlock, Sarah Menig, Olga Militano, Bonnie Ky, Chad A. Hudson, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi, Anders Kolb, and Todd M Cooper

Program: Oral and Poster Abstract, Acute Myeloid Leukemias: Commercially Available Therapies: Optimizing Regimens in Children/Young Adults and Around the World

Poster Session: December 9, 4:30 PM PST | Session 617 (Number 967)